Not merely its amount but also the purposeful Homes of Hb influence efficiency. This is often illustrated with the observation that an elevated Hb-O2 affinity favors O2 loading while in the lung and survival in an hypoxic setting (Eaton et al., 1974; Hebbel et al., 1978), whereas a reduced Hb-O2 affinity favors the release of O2 through the Hb mole
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